Saxenda® includes liraglutide and shouldn't be coadministered with other liraglutide-made up of products or with any other GLP-1 receptor agonist The protection and performance of Saxenda® in pediatric people with type two diabetes haven't been recognized
liraglutide, insulin aspart protamine/insulin aspart. Either raises consequences of the other by pharmacodynamic synergism. Use Warning/Watch. Antidiabetic agents are frequently used in combination; dosage adjustments could possibly be required when initiating or discontinuing antidiabetic agents.
liraglutide, insulin detemir. Either increases results of the opposite by pharmacodynamic synergism. Use Caution/Keep track of. Antidiabetic agents in many cases are applied together; dosage adjustments might be necessary when initiating or discontinuing antidiabetic agents.
Observe Closely (1)levonorgestrel oral decreases outcomes of liraglutide by pharmacodynamic antagonism. Use Caution/Monitor. Oral contraceptives may reduce hypoglycemic outcomes of antidiabetics by impairing glucose tolerance. Watch for glycemic Manage in diabetic people.
Thiazide diuretics can decrease insulin sensitivity therefore resulting in glucose intolerance and hyperglycemia. Check glycemic control specially when initiating, discontinuing, or increasing thiazide diuretic dose.
triamcinolone acetonide injectable suspension decreases consequences of liraglutide by pharmacodynamic antagonism. Use Caution/Check. Corticosteroids may perhaps diminish hypoglycemic effect of antidiabetic brokers. Check blood glucose amounts carefully. .
liraglutide, insulin degludec/insulin aspart. Both improves outcomes of one other by pharmacodynamic synergism. Use Warning/Check. Antidiabetic agents tend to be used in combination; dosage adjustments could be necessary when initiating or discontinuing antidiabetic brokers.
Keep an eye on Intently (1)liraglutide, insulin regular human. Both will increase results of one other by pharmacodynamic synergism. Use Warning/Monitor. Antidiabetic agents are often utilized together; dosage adjustments may very well be essential when initiating or discontinuing antidiabetic agents.
, the most serious warning from the Foodstuff and Drug Administration (FDA). A boxed warning alerts Medical doctors and sufferers about drug effects Which might be risky. This medication might boost your risk of thyroid most cancers. This aspect result occurred in animal scientific studies but hasn’t been documented in individuals right now. Animal scientific studies don’t always show what may possibly materialize in human beings. As a result of this threat, Physicians ordinarily won’t prescribe this medication Should you have a private or relatives background of medullary thyroid most cancers (MTC).
liraglutide will decrease the level or outcome of atorvastatin by Other (see remark). Use Caution/Observe. Determined by pharmacokinetic experiments liraglutide decreased atorvastatin Cmax by 38% and median Tmax delayed from 1h to 3h with liraglutide plus the AUC did not transform.
liraglutide, insulin degludec. Possibly boosts effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Antidiabetic agents are sometimes applied in combination; dosage changes might be necessary when initiating or discontinuing antidiabetic brokers.
Thiazide diuretics can minimize insulin sensitivity thus bringing about glucose intolerance and hyperglycemia. Keep an eye on glycemic Regulate especially when initiating, discontinuing, or growing thiazide diuretic dose.
Appraise the improve in entire body fat sixteen weeks just after initiating SAXENDA and discontinue SAXENDA Should the affected person has not missing no less than 4% of baseline physique weight, because it is not likely which the patient will achieve and maintain clinically meaningful fat loss with continued treatment method.
The commonest Uncomfortable side effects incorporate nausea, vomiting, diarrhea, constipation, more info and pores and skin reactions within the injection site. The good news is, these Unwanted effects normally get better by themselves over time. But in the event you locate the Unwanted side effects much too unpleasant, you are able to often drop again all the way down to the decrease dose and check out the upper dose once more later.